Research

Hoshi CorporationNew! Efficacy on Breast Skin Tension of the Supplement Containing Pueraria Mirifica in Healthy Japanese Females: A Randomized, Double-blind, Placebo-controlled StudyM. NAJIMA, A. MIYATA, H. SASAGAWA

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Hoshi CorporationNew! Efficacy on Menopausal Discomfort of the Supplement Containing Pueraria Mirifica in Healthy Japanese Females: A Randomized, Double-blind, Placebo-controlled StudyM. NAJIMA, M. MUNEKATA, H. SASAGAWA

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Hoshi CorporationNew! Pueraria mirifica alleviates cortical bone loss in naturally menopausal monkeysDr. Suchinda Malaivijitnond, Chulalongkorn university

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Hoshi CorporationAn Interview of Pueraria mirifica and Reducing Cancer Risk with Professor Margaret RitchieRichard A. Passwater, Ph.D.

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Hoshi CorporationAn interview of Menopause and Pueraria mirifica with Christiane Northrup, M.D.Richard A. Passwater, Ph.D.

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Hoshi CorporationNeurotherapeutic Effects of Pueraria mirifica Extract in Early- and Late-State Cognitive Impaired RatsKanya Anukulthanakorn, Ishwar S. Parhar, Sukanya Jaroenporn, Takashi Kitahashi, Gen Watanbe and Suchinda Malaivijitnond

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Hoshi CorporationAnti-osteoporotic effects of Pueraria candollei var. mirifica on bone mineral density and histomorphometry in estrogen-deficient rats.Dr. Suchinda Malaivijitnond, Chulalongkorn university

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Hoshi CorporationRegulation of cancer-related genes – Cyp1a1, Cyp1b1, Cyp19, Nqo1 and Comt – expression in β -naphthoflavone-treated mice by miroestrol.Dr. Kanokwan Jarukamjorn,Khon Kaen university

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Hoshi Corporation
Pueraria mirifica extract and puerarin enhance proliferation and expression of alkaline phosphatase and type I collagen in primary baboon osteoblasts
Wacharaporn Tiyasatkulkovit, suchinda Malaivijitnond, Narattaphol Charoenphandhu, Lorena Havill, Allen Ford, John VandeBert. PHYTOMEDICINE JOURNAL JUNE 27 2014

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Hoshi CorporationCytotoxic Activity of the Pueraria mirifica on the Oral Cancer Cell Line ORL48T.Wacharaporn Tiyasatkulkovit, suchinda Malaivijitnond, Narattaphol Charoenphandhu, Lorena Havill, Allen Ford, John VandeBert. PHYTOMEDICINE JOURNAL JUNE 27 2014

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Hoshi Corporation
Pueraria mirifica extract and puerarin enhance proliferation and expression of alkaline phosphatase and type 1 collagen in primary baboon osteoblasts.
Wacharaporn Tiyasatkulkovit, suchinda Malaivijitnond, Narattaphol Charoenphandhu, Lorena Havill, Allen Ford, John VandeBert. PHYTOMEDICINE JOURNAL JUNE 27 2014

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Hoshi CorporationPreventive effect of Pueraria mirifica on testosterone-induced prostatic hyperplasia in Sprague Dawley rats.S. S. Masrudin & J Mohamad. INSTITUTE OF BIOLOGICAL SCIENCES, FACULTY OF SCIENCE, UNIVERSITY OF MALAYSA. NOVERMBER 13, 2014

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Hoshi CorporationDuration of Menopausal Vasomotor Symptoms Over the Menopause Transition.PhD, Sybil L. Crawford, PhD, Gail Greendale, MD, Joyce T. Bromberger, PhD, Susan A. Everson-Rose, Phd, MPH, Ellen B. Gold, PhD, Rachel Hess, MD, Hadine Joffee, MD, MSc, Howard M. Kravitz, DO, MPH, Ping G. Tepper, PhD, Rebecca C. Thurston, PhD. THE STUDY OF WOMEN’S HEALTH ACROSS THE NATION, jama Intern Med February 16, 2015.

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Hoshi CorporationPhase I: Preliminary Report on Challenges in the Conduct of Thai Herbal Scientific Study: Efficacy and Safety of Phytoestrogen, Pueraria Mirifica (Kwao Keur Kao), Phase I, in the Alleviation of Climacteric Symptoms in Perimenopausal Women.By Verapol Chandeying, MD and Surachai Lamlertkittikul, MD.

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Phase II: Safety of Pueraria mirifica (Kwao Keur Kao) for the Treatment of Vasomotor Symptoms in Perimenopausal Women: Phase II Study

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Phase III: Efficacy Comparison of Pueraria Mirifica (PM) against Conjugated Equine Estrogen (CEE) with/without Medroxyprogesterone Acetate (MPA) in the Treatment of Climacteric Symptoms in Perimenopausal Women: Phase III Study.By Verapol Chandeying, MD and Malinee Sangthawan, MD.

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Hoshi Corporation
Effect of Pueraria Mirifica on Vaginal Health
Jittima Manonai, MD, Apichart Chittacharoen, MD, Urusa Theppisai, MD & Hathai Theppisai, MD. THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY Vol. 14, No. 5

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Hoshi CorporationObscure Thai “super herb” beats Big Pharma’s hormone replacement therapy.Health Sciences Institute, April 2008, Melissa Hickle

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Review of the Efficacy, Safety and Applications, of Pueraria candollei var.mirifica Airy Shaw root: A Unique Thai Botanical Medicine with Potential as a U.S. Dietary Supplement for Oral and Topical Use. Alexander G. Schauss, PhD, Director, Natural and Medicinal Products Research, Life Sciences Division, American Institute for Biosocial and Medical Research, Inc., Puyallup, Washington

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Hoshi CorporationPhyto-estrogens: Do They Have a Role in Breast Cancer Therapy?S. Ramnarine, J. MacCallum and M. Ritchie, Edinburgh Univesity, Edinburgh, UK and Napier University, Edinburgh, UK

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Phytoestrogens and Breast Cancer Risk. Review of the epidemiological evidence.R Peeters PH1, Keinan-Boker L, van der Schouw YT, Grobbee DE. Julius Center for Health Studies and Primary Care, University Medical Center Utrecht, The Netherlands.

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The Safety of Phytoestrogens in Menopause, Prostate & Breast CancerJill Stansbury, NDa, Paul Richard Sanders, PhD, ND, DHANPb, David Winston, RH (ACH)c JOURNAL OF RESTORATIVE MEDICINE, 2013

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Hoshi CorporationMiroestrol, a phytoestrogen from Pueraria Mirifica, improves the antioxidation state in the livers and uteri of B-naphthoflavone-treated mice.Nattharat Jearapong, Waranya Chatuphonprasert & Dr. Kanokwan Jarukamjorn J NAT MED – Original Paper

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Inhibitory Potentials of Five Phytoestrogens from Pueraria candokkei var. mirifica on CYP1A1 and CYP1A2 Proteins in Mouse Liver Microsomes and in silico.Waranya Chatuphonprasert, Kanokwan Jarukanjorn, Waraporn Putalun and Thaweesak Juengwattanatrakul

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Hoshi CorporationImprovements of vaginal atrophy without systemic side effects after topical application of Pueraria Mirifica, a phytoestrogen-rich herb, in postmenopausal cynomolgus macaques.Sukanya Jaroenporn, Nontakorn Urasopon, Gen Watanabe & Suchinda Malaivijitnond JOURNAL OF REPRODUCTION & DEVELOPMENT

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Phytoestrogens: Epidemiology and a Possible Role in Cancer ProtectionHerman Adlercreutz, Department of Clinical Chemistry, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Upregulation of osteoblastic differentiation marker mRNA expression in osteoblast-like UMR106 cells by puerarin and phytoestrogens from Pueraria MirificaWacharaporn Tiyasatkulkovit, Narattaphol Charoenphandhu, Kannikar Wongdee, Jirawan Thongbunchoo, Nateetip Krishnamara & Suchinda Malaivijitnond. PHYTOMEDICINE JOURNAL

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Effects of Pueraria Mirifica and miroestrol on the antioxidation-related enzymes in ovariectomized mice. Waranya Chatuphonprasert, Latiporn Udomsuk, Orawan Monthakantirat, Yaowared Churkhit, Waraporn Putalun & Dr. Kanokwan Jarukamjorn. JOURNAL OF PHARMACY & PHARMACOLOGY

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Hoshi CorporationDown regulation of gene related sex hormone synthesis pathway in mouse testes by miroestrol and deoxymiroestrol.Latiporn Udomsuk, Thaweesak Juengwatanatrakul, Waraporn Putalun, & Dr. Kanokwan Jarukamjorn. ELSEVIER NUTRITION RESEARCH

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Phytoestrogen-Puresterol (Pueraria Mirifica) in the alleviation of climacteric symptoms.Ta-Chin Lin & Tsung-Cheng Kuo Departments of Gynecology, Obstetrics & Infertility, Kuo General Hospital.

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Preliminary study of Pueraria mirifica in Japanese.Prof. Kuramoshi, Assoc. Prof Yuthana Smitasiri, School of Medicine, Saint Mariane University, Tokyo, Japan.

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Studies on the Toxicity of Pueraria mirifica in Tripala-related Female Rats.Yuthana Smitasiri, Nirush Lertprasertsuk, Athipong Manasathien, Witthisak Pinmongkhongul, Alex Schauss. MAE FAH LUANG UNIVERSITY, AMPHOR MUANG, CHIANG-RAI PROVINCE.

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Bacterial Reverse Mutation (Ames) Test of Pueraria mirifica, PE.Pharmaceutical Control and Development Laboratory Co., Ltd. Final Report

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An ancient Thai “miracle” herb reveals itself to be a real-life fountain of youth.Alicia Potee. HEALTH SCIENCES INSTITUTE SEPTEMBER 2007, VOL. 12, NO. 3.

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Puerarin reduces endothelial progenitor cells senescence through augmentation of telomerase activity.By: JunHui Zhu, XingXiang Want, YunPeng Sang, XuDong Xie, FuRong Whang, JunZhu Chen, GuoSheng Fu. Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejian University, Department of Cardiology, the First Affiliated Hospital, College of Medicine, Ahejian University.

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Additional Resources

Schwartz – Pueraria Mirifica -True Lies & Scientific Truth – Part II

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Is Pueraria Mirfica the Ideal Phyto-oestrogen Needed for Menopause and More – Garry Gordon, MD, DO

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Inhibitory Potentials of Five Phytoestrogens from Pueraria candollei var. mirifica on CYP1A1 and CYP1A2 Proteins in Mouse Liver Microsomes and in silico

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An ancient Thai “miracle” herb reveals itself to be a real-life fountain of youth Health Sciences Institute, September 2007

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Keith Scott-Mumby MD, PhD. – Pueraria Mirifica “The Real Life Fountain Of Youth” Herbal remedy from Thailand >>ISSUE 1. Date: March 1st 2013

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Keith Scott-Mumby MD, PhD – Miracle HRT VDO about Pueraria Mirifica by Keith Scott-Mumby MD, PhD.

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Challenges in the Conduct of Thai Herbal Scientific Study: Efficacy and Safety of Phytoestrogen, Pueraria Mirifica (Kwao Keur Kao), Phase I, in the Alleviation of Climacteric Symptoms in Perimenopausal Women By Verapol Chandeying and Surachai Lamlertkittikul

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Hoshi CorporationDr.Robert Jay Rowen’s Second opinion “Unique Plant from Thailand Stops Hot Flashes,Bone Loss, and Slows Aging”

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